Remember to use it at the same time each day. Tell your doctor if your condition worsens. Side Effects See also Warning section. Stomach upset, nausea , dizziness , or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.
Tell your doctor right away if you have any serious side effects, including: This drug may rarely cause serious possibly fatal liver disease. Get medical help right away if you have any symptoms of liver damage, including: A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: This is not a complete list of possible side effects. The use of MOBIC for the treatment of the signs and symptoms of rheumatoid arthritis was evaluated in a week double-blind, controlled multinational trial.
The primary endpoint in this study was the ACR20 response rate, a composite measure of clinical, laboratory and functional measures of RA response. No incremental benefit was observed with the Pauciarticular and Polyarticular Course Juvenile Rheumatoid Arthritis JRA The use of MOBIC for the treatment of the signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis in patients 2 years of age and older was evaluated in two week, double-blind, parallel-arm, active-controlled trials.
Both studies included three arms: In both studies, meloxicam dosing began at 0. One study used these doses throughout the week dosing period, while the other incorporated a titration after 4 weeks to doses of 0. The efficacy analysis used the ACR Pediatric 30 responder definition, a composite of parent and investigator assessments, counts of active joints and joints with limited range of motion, and erythrocyte sedimentation rate.
The proportion of responders were similar in all three groups in both studies, and no difference was observed between the meloxicam dose groups. Patients with known CV disease or risk factors for CV disease may be at greater risk. To minimize the potential risk for an adverse CV event in patients treated with an NSAID, the lowest effective dose should be used for the shortest duration possible.
Physicians and patients should remain alert for the development of such events, even in the absence of previous CV symptoms. There is no consistent evidence that concurrent use of aspirin mitigates the increased risk of serious CV thrombotic events associated with NSAID use.
Patients taking thiazides or loop diuretics may have impaired response to these therapies when taking NSAIDs. These serious adverse events can occur at any time, with or without warning symptoms, in patients treated with NSAIDs.
These trends continue with longer duration of use, increasing the likelihood of developing a serious GI event at some time during the course of therapy. However, even short-term therapy is not without risk. NSAIDs should be prescribed with extreme caution in those with a prior history of ulcer disease or gastrointestinal bleeding. The use of these for long-term treatment of rheumatoid medicines at the same time as meloxicam is arthritis or ankylosing spondylitis is 7.
Also, patients at high risk of side effects should start treatment with 7. If you have severe kidney dysfunction and During the first 6 months of pregnancy your receive dialysis, the maximum dose of meloxicam should be 7. If you take more Meloxicam than you During the last three months of pregnancy, should do not use this product because meloxicam Symptoms of overdose are usually limited to lethargy, drowsiness, nausea, vomiting can have serious effects on your child, in and pain in the stomach.
These symptoms particular cardiopulmonary and renal are generally reversible. If you forget to take Mobic Tablets do not take a double dose to make up for the missed dose. If after several days you do not feel any improvement in your condition then you should talk to your doctor or pharmacist. Side-effects All medicines can cause side effects. The side effects described below have been experienced by people taking meloxicam and they are listed as either common, uncommon or rare.
Side effects associated with the digestive system stomach and intestines Common: If you have a history of gastrointestinal symptoms whilst taking antiinflammatory drugs, your doctor may monitor your progress whilst on treatment.
Side effects associated with the skin Common: Side effects associated with the eye Rare: Side effects associated with the cardiovascular system Common: Asthma attacks seen in people who are allergic to aspirin or other non-steroidal antiinflammatory drugs If you suffer from an allergic reaction or asthma attack after taking Mobic Tablets, seek medical advice immediately. Meloxicam comes with an extra patient information sheet called a Medication Guide.
Read it again each time you get Meloxicam refilled. Take Meloxicam by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems eg, bleeding, ulcers. Talk with your doctor or pharmacist if you have persistent stomach upset. If you take cholestyramine, ask your doctor or pharmacist how to take it with Meloxicam. If you miss a dose of Meloxicam , take it as soon as possible.
If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. The pharmacological activity of meloxicam in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions.
These laboratory abnormalities may progress, may remain unchanged, or may be transient with continuing therapy. In addition, rare cases of severe hepatic reactions, including jaundice and fatal fulminant hepatitis, liver necrosis and hepatic failure, some of them with fatal outcomes have been reported. If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur e.
Renal Effects Caution should be used when initiating treatment with meloxicam in patients with considerable dehydration. It is advisable to rehydrate patients first and then start therapy with meloxicam. The extent to which metabolites may accumulate in patients with renal failure has not been studied with meloxicam. Because some meloxicam metabolites are excreted by the kidney, patients with significantly impaired renal function should be more closely monitored.
This may be due to fluid retention, occult or gross GI blood loss, or an incompletely described effect upon erythropoiesis. Patients on long-term treatment with NSAIDs, including meloxicam, should have their hemoglobin or hematocrit checked if they exhibit any signs or symptoms of anemia.
Drugs which inhibit the biosynthesis of prostaglandins may interfere to some extent with platelet function and vascular responses to bleeding.
NSAIDs inhibit platelet aggregation and have been shown to prolong bleeding time in some patients. Unlike aspirin their effect on platelet function is quantitatively less, of shorter duration, and reversible. Patients receiving meloxicam who may be adversely affected by alterations in platelet function, such as those with coagulation disorders or patients receiving anticoagulants, should be carefully monitored.
Pre-existing Asthma Patients with asthma may have aspirin-sensitive asthma. The use of aspirin in patients with aspirin-sensitive asthma has been associated with severe bronchospasm which can be fatal. Since cross reactivity, including bronchospasm, between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, meloxicam should not be administered to patients with this form of aspirin sensitivity and should be used with caution in patients with pre-existing asthma.
Information for Patients Patients should be informed of the following information before initiating therapy with an NSAID and periodically during the course of ongoing therapy. Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative sign or symptoms.
Meloxicam, like other NSAIDs, can cause GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, which may result in hospitalization and even death.
Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptoms including epigastric pain, dyspepsia, melena, and hematemesis.
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