To treat high blood pressure, the recommended adult dose is 80 mg once daily. To treat heart failure, the recommended starting dose is 40 mg twice daily.
The maximum recommended dose is mg twice daily. After a heart attack, the recommended starting dose of valsartan is 20 mg twice daily. Your doctor may increase the dose slowly over 1 to 2 weeks to a target dosage of mg twice daily. Precautions Before taking Diovan you should talk with your doctor if you have kidney or liver problems, low blood pressure, congestive heart failure, glaucoma, if you are allergic to sulfa drugs or penicillin, breastfeeding. It can lower your blood pressure and may increase some of the side effects.
Contraindications Do not take Diovan if you are allergic to valsartan or to any of the ingredients of the medication, or pregnant. Every effort has been made to ensure that the information provided by on this page is accurate, up-to-date, and complete, but no guarantee is made to that effect.
Drug information contained herein may be time sensitive. The information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Calcium excretion is decreased by thiazide diuretics. This may result in hypercalcaemia. As for any patient receiving diuretic therapy, periodic determination of serum electrolytes should be performed at appropriate intervals. Patients with severe chronic heart failure or other conditions with stimulation of the renin-angiotensin-aldosterone-system In patients whose renal function may depend on the activity of the renin-angiotensin-aldosterone system e. Evaluation of patients with heart failure or post-myocardial infarction should always include assessment of renal function.
The use of Co-Diovan in patients with severe chronic heart failure has not been established. Hence it cannot be excluded that because of the inhibition of the renin-angiotensin-aldosterone system the application of Co-Diovan as well may be associated with impairment of the renal function. Co-Diovan should not be used in these patients.
Renal artery stenosis Co-Diovan should not be used to treat hypertension in patients with unilateral or bilateral renal artery stenosis or stenosis of the artery to a solitary kidney, since blood urea and serum creatinine may increase in such patients. Primary hyperaldosteronism Patients with primary hyperaldosteronism should not be treated with Co-Diovan as their renin-angiotensin system is not activated.
Aortic and mitral valve stenosis, hypertrophic obstructive cardiomyopathy As with all other vasodilators, special caution is indicated in patients suffering from aortic or mitral stenosis, or hypertrophic obstructive cardiomyopathy HOCM.
Periodic monitoring of serum potassium, creatinine and uric acid levels is recommended when Co-Diovan is used in patients with renal impairment.
Kidney transplantation There is currently no experience on the safe use of Co-Diovan in patients who have recently undergone kidney transplantation. Hepatic impairment In patients with mild to moderate hepatic impairment without cholestasis, Co-Diovan should be used with caution see sections 4. Thiazides should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.
Co-Diovan should be immediately discontinued in patients who develop angioedema, and Co-Diovan should not be re-administered see section 4. Systemic lupus erythematosus Thiazide diuretics, including hydrochlorothiazide, have been reported to exacerbate or activate systemic lupus erythematosus.
Other metabolic disturbances Thiazide diuretics, including hydrochlorothiazide, may alter glucose tolerance and raise serum levels of cholesterol, triglycerides and uric acid. In diabetic patients dosage adjustments of insulin or oral hypoglycaemic agents may be required. Thiazides may reduce urinary calcium excretion and cause an intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism.
Marked hypercalcaemia may be evidence of underlying hyperparathyroidism. Thiazides should be discontinued before carrying out tests for parathyroid function. Photosensitivity Cases of photosensitivity reactions have been reported with thiazide diuretics see section 4. If photosensitivity reaction occurs during treatment, it is recommended to stop the treatment. If a re-administration of the diuretic is deemed necessary, it is recommended to protect exposed areas to the sun or to artificial UVA.
Unless continued AIIRAs therapy is considered essential, patients planning pregnancy should be changed to alternative anti-hypertensive treatments which have an established safety profile for use in pregnancy. When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately, and, if appropriate, alternative therapy should be started see sections 4. General Caution should be exercised in patients who have shown prior hypersensitivity to other angiotensin II receptor antagonists.
Hypersensitivity reactions to hydrochlorothiazide are more likely in patients with allergy and asthma. Acute Angle-Closure Glaucoma Hydrochlorothiazide, a sulfonamide, has been associated with an idiosyncratic reaction resulting in acute transient myopia and acute angle-closure glaucoma. As a result, the medication is also helpful in preventing heart attacks and damage caused by diabetes, apart from treating hypertension or high blood pressure.
Chest pain, fast heartbeat, numbness, fainting, weakness, swelling and dry mouth are other possible side effects that may occur.
Less common Diovan HCT side effects may include insomnia, headache, anxiety, loss of appetite, diarrhea, constipation, skin rashes and itching, sore throat, cough and loss of interest in sex. Most of these side effects have been reported by only a few patients using the medication. Discuss them with your doctor before you buy Diovan HCT and report their occurrence while using it.
Precautions Due to the possible damage that Diovan HCT can cause to a fetus, the medication is not prescribed for pregnant women. Though its side effects for a nursing mother have not been established, you must talk to your doctor if you are breastfeeding. Patients suffering from liver and kidney disorders, diabetes and allergies and those who have had congestive heart failure in the past should discuss the same with their doctors before using the medication.
It is important to monitor your blood pressure regularly while taking Diovan HCT.
Caution is advised in long-term administration of these drugs. If you notice other effects not listed above, contact your doctor. Infants whose mothers have taken AIIRAs should be closely observed for hypotension see also section 4. Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to week of a drug initiation. What differences are there price generic and brand? Dual Blockade of the Renin-Angiotensin-Aldosterone System RAAS There is diovan that the concomitant use of ACE inhibitors, angiotensin II receptor blockers or aliskiren increases the risk of hypotension, diovan uk prices, hyperkalaemia, and decreased renal function including acute renal failure. Prompt medical or surgical treatment may need to be considered if the intraocular pressure remains uncontrolled. Valsartan is an angiotensin receptor blocker that helps in the relaxation of blood vessels. Renal artery stenosis Co-Diovan should not be used to treat hypertension in patients with unilateral or bilateral renal artery stenosis or stenosis of the artery to a solitary kidney, since blood urea and serum creatinine may increase in such patients.
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