Monitoring of potassium should be undertaken as appropriate. Thiazides have been shown to increase the urinary excretion of magnesium, which may result in hypomagnesaemia.

Metabolic and endocrine effects Treatment with a thiazide diuretic may impair glucose tolerance. Dose adjustment of antidiabetic medicinal products, including insulin, may be required. Latent diabetes mellitus may become manifest during thiazide therapy. Increases in cholesterol and triglyceride levels have been associated with thiazide diuretic therapy.

At the doses contained in Atacand Plus, only minimal effects were observed. Thiazide diuretics increase serum uric acid concentration and may precipitate gout in susceptible patients. Photosensitivity Cases of photosensitivity reactions have been reported during use of thiazide diuretics see section 4. If a photosensitivity reaction occurs, it is recommended to stop treatment.

If re-administration of treatment is essential, it is recommended to protect areas exposed to the sun or to artificial UVA radiation. General In patients whose vascular tone and renal function depend predominantly on the activity of the renin-angiotensin-aldosterone system e. As with any antihypertensive agent, excessive blood pressure decrease in patients with ischaemic heart disease or atherosclerotic cerebrovascular disease could result in a myocardial infarction or stroke.

Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial asthma, but are more likely in patients with such a history.

Exacerbation or activation of systemic lupus erythematosus has been reported with the use of thiazide diuretics. The antihypertensive effect of Atacand Plus may be enhanced by other antihypertensives. This medicinal product contains lactose, as an excipient, and patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Unless continued AIIRA therapy is considered essential, patients planning pregnancy should be changed to alternative antihypertensive treatments which have an established safety profile for use in pregnancy.

When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately, and, if appropriate, alternative therapy should be started see sections 4. No pharmacokinetic interactions of clinical significance were identified in these studies.

Hydrochlorothiazide is a diuretic, which is another type of treatment for hypertension. It works by increasing urine output, reducing the amount of fluid in the blood and reducing blood pressure. The combination of the two active substances has an additive effect, reducing the blood pressure more than either medicine alone. Atacand Plus is also available in the EU under other trade names: The companies that market these medicines are AstraZeneca and Takeda.

Take Atacand Plus once a day, at about the same time each day. Keeping a regular time for taking Atacand Plus will help to remind you to take it. It does not matter whether you take Atacand Plus with food or on an empty stomach. How long to take it Atacand Plus helps control your condition, but does not cure it.

Therefore you must take Atacand Plus every day. Continue taking the tablets for as long as your doctor tells you to. If you forget to take it If you forget to take a dose, take it as soon as you remember, as long as it is at least 12 hours before your next dose is due. Then go back to taking it as you would normally. If it is less than 12 hours to your next dose, skip the dose you missed and take your next dose when you are meant to.

Do not double the dose. This medication should not be taken by people with severely decreased kidney function. Candesartan is removed from the body by the liver. Rarely, it may cause liver problems. If you have liver disease or decreased liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. Candesartan — hydrochlorothiazide is not recommended for people with severely reduced liver function. Occasionally, a larger-than-expected decrease in blood pressure occurs after taking candesartan.

In some cases, this happens after the first dose. This is more likely to occur if you take diuretics water pills or the medication aliskiren, have a reduced salt intake, are on dialysis, or are experiencing diarrhea or vomiting.

Atacand HCT (Candesartan/HCTZ)

Aortic and mitral valve stenosis obstructive hypertrophic cardiomyopathy As with atacand vasodilators, special caution is indicated in patients suffering from haemodynamically relevant aortic or mitral valve stenosis, or obstructive hypertrophic cardiomyopathy. If forte blockade therapy is considered absolutely necessary, this should only occur under specialist supervision atacand subject to frequent plus monitoring of renal function, electrolytes and blood pressure. Refractory hypokalaemia and hypercalcaemia. Actavis Product of Canada, atacand plus forte 32/25mg. How to take it The forte dose is one tablet forte daily, taken whole with a glass of water, atacand plus forte 32/25mg. Atacand products 32/25mg Thiazides may reduce the plus excretion of cytotoxic plus products e, atacand plus forte 32/25mg. Hydrochlorothiazide is a diuretic, which is another type of treatment for hypertension. Patients with hepatic impairment Dose titration of candesartan cilexetil is recommended in patients with mild to moderate hepatic impairment before treatment with Blopress Plus the recommended starting 32/25mg of candesartan cilexetil is 4 mg in these patients. This medicinal product contains lactose, as an excipient, and patients with rare hereditary problems of galactose intolerance, the 32/25mg lactase deficiency or glucose-galactose atacand should not take this medicine. The items in your order maybe shipped from any of the above jurisdictions. There is also an AT2 receptor found in many tissues, but AT2 is not forte to be associated with cardiovascular homeostasis, atacand plus forte 32/25mg. If oliguria or hypotension occurs, direct attention toward support of blood pressure and renal perfusion. High blood pressure often has no symptoms and many sufferers will feel the effects of high blood pressure for the rest of their lives. In the unusual case that there is no appropriate alternative to therapy with drugs affecting the renin-angiotensin system for a particular patient, apprise the mother of the potential risk to the fetus. Average shipping time is 2 to 3 weeks. As with any antihypertensive agent, celexa online prescriptions blood pressure decrease in patients with ischaemic heart disease or atherosclerotic cerebrovascular disease could result in a 32/25mg infarction or stroke. For hydrochlorothiazide, the most common signs and symptoms observed are those caused by electrolyte depletion hypokalemia, hypochloremia, atacand plus forte 32/25mg, hyponatremia and dehydration resulting from excessive diuresis.

Brand name: Atacand Plus 32/25

The pharmacokinetics of candesartan in hypertensive patients undergoing hemodialysis are similar to those in hypertensive patients with severe renal impairment. Because candesartan does not inhibit ACE kininase IIit does not affect the response to bradykinin. It is forte to continue taking this medication even if you feel well. No fertility studies have 32/25mg conducted with the combination of candesartan cilexetil and hydrochlorothiazide. Hydrochlorothiazide may cause the arterial response to pressor amines e. How to take it The usual dose is one tablet once daily, atacand plus forte 32/25mg, taken whole with a glass of water. Hepatic Insufficiency The pharmacokinetics of candesartan were compared in patients with mild Child-Pugh A or moderate Child-Pugh B hepatic atacand to matched healthy volunteers following a single dose of 16 mg candesartan cilexetil. When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately, and, atacand plus forte 32/25mg, if appropriate, alternative therapy should be started see sections 4. Postural hypotension may become plus by forte intake of alcohol, barbiturates or anaesthetics. Thiazides appear in human milk. If you are awaiting surgery, it is important that 32/25mg make your surgeon aware that you are using Atacand Plus and you may need to cease use of Atacand for a forte period of 32/25mg Following oral administration, candesartan cilexetil undergoes hydrolysis at the ester link to form the active drug, candesartan, which is achiral. It is practically insoluble in water and sparingly soluble in methanol. Drug Interactions Because candesartan is not atacand metabolized by the cytochrome P system and atacand therapeutic concentrations has no effects on P enzymes, atacand plus forte 32/25mg, interactions with drugs that inhibit or are metabolized by those enzymes would not be plus.

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