Me being the typical me, with my chronic lack of abiltity to concentrate and devote my attention to school, I was very intrigued by his description of this supposed 'wonder pill'. Being my generally reckless and risk-taking self, I didn't bother to even read up on this drug I'd never even heard the name of before before I decided it was time to set it into action. While my dealer sincerely cautioned me, I assured him I knew that I could handle it not truly even grasping the concept of what 'it' was , and I bought one 30mg and downed it in the school bathroom during lunch.
Thus began a strange, twisted sort of relationship with my first truly abuseable drug. By the time the middle of my next class hit, I could tell something was 'different'. I couldn't quite put my finger on it, but suddenly all that chemistry homework just couldn't wait until after school to get done and that report outline needed touch-up RIGHT NOW.
I glued my face to the paper, the pencils went flying, and in what felt like 30 seconds the class was over The school day was over in what felt to me like about 15 minutes of my day. For those 20 minutes I had the strangest feeling people were staring at 'the freak doing homework on the bus', but the other effect of the Adderall, the mild-moderate euphoria, masked that paranoia I started taking 30 mg a day every 2 or 3 days.
Spiralling down the slippery slope, the 'normal me' just couldn't cut it for any part of the day, and I stopped putting in those days between doses. Then the doses stopped lasting as long. I'd take 2, and soon thereafter 3, doses a day to keep myself 'functional'.
By then I had realized I was rapidly becoming psychologically addicted to this drug, but my priorities were set to me so that my health and well-being could suffer if it meant the betterment of my grades. Then the doses increased. I was on about 60 mg a day, then 90 mg. It got to the point that I actually took mg at once one day my tolerance had skyrocketed so much. Lucky me, I had never really experienced much of a crash aside from the general disappointment over the end of a good speed high.
My dosing continued even outside of school, I found that this pill had its recreational benefits. On weekends I didn't feel like having the usual friends over to smoke weed, I would load up on Adderall the Friday thereof, and suddenly I had the energy to have any kind of fun I wanted until my tedious work program resumed the following Monday. I would have just as good a high on Adderall as on dexies Dexedrine , which I promptly tried with the intention of comparing to Adderall.
This is where the real problems started setting in. Noticing that the cost of living was getting more and more obscenely pricey Adderall usually doesn't run cheap where I live , I began to have paranoid fits, even when high on Adderall. Amphetamines are thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space.
Pharmacokinetics Pharmacokinetic studies of Adderall XR have been conducted in healthy adult and pediatric children aged yrs subjects, and adolescent yrs and children with ADHD. Following administration of ADDERALL immediate-release , the peak plasma concentrations occurred in about 3 hours for both d-amphetamine and l-amphetamine. This is consistent with the extended-release nature of the product.
A single dose of Adderall XR 20 mg capsules provided comparable plasma concentration profiles of both d-amphetamine and l-amphetamine to ADDERALL immediate-release 10 mg twice daily administered 4 hours apart. For the l-amphetamine, the mean elimination half-life in adults is 13 hours; 13 to 14 hours in adolescents; and 11 hours in children aged 6 to 12 years. There is no unexpected accumulation at steady state in children.
Food does not affect the extent of absorption of d-amphetamine and l-amphetamine, but prolongs Tmax by 2. Opening the capsule and sprinkling the contents on applesauce results in comparable absorption to the intact capsule taken in the fasted state. Equal doses of Adderall XR strengths are bioequivalent. Norephedrine and 4-hydroxy-amphetamine are both active and each is subsequently oxidized to form 4-hydroxy-norephedrine.
Alpha-hydroxy-amphetamine undergoes deamination to form phenylacetone, which ultimately forms benzoic acid and its glucuronide and the glycine conjugate hippuric acid. Although the enzymes involved in amphetamine metabolism have not been clearly defined, CYP2D6 is known to be involved with formation of 4-hydroxy-amphetamine.
Since CYP2D6 is genetically polymorphic, population variations in amphetamine metabolism are a possibility. Amphetamine is known to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit various P isozymes and other enzymes has not been adequately elucidated. However, due to the probability of auto-inhibition and the lack of information on the concentration of these metabolites relative to in vivo concentrations, no predications regarding the potential for amphetamine or its metabolites to inhibit the metabolism of other drugs by CYP isozymes in vivo can be made.
Since amphetamine has a pKa of 9. Alkaline urine pHs result in less ionization and reduced renal elimination, and acidic pHs and high flow rates result in increased renal elimination with clearances greater than glomerular filtration rates, indicating the involvement of active secretion.
Consequently, both hepatic and renal dysfunction have the potential to inhibit the elimination of amphetamine and result in prolonged exposures. Special Populations Comparison of the pharmacokinetics of d- and l-amphetamine after oral administration of Adderall XR in children years and adolescent years ADHD patients and healthy adult volunteers indicates that body weight is the primary determinant of apparent differences in the pharmacokinetics of d- and l-amphetamine across the age range.
Age and gender had no direct effect on the pharmacokinetics of d- and l-amphetamine. Race Formal pharmacokinetic studies for race have not been conducted. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment of Fertility No evidence of carcinogenicity was found in studies in which d,l-amphetamine enantiomer ratio of 1: Check your blood pressure regularly and tell your doctor if the results are high. Tell your doctor right away if you have any serious side effects, including: Get medical help right away if you have any very serious side effects, including: The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take see Drug Interactions section.
Get medical help right away if you develop some of the following symptoms: A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at List Adderall side effects by likelihood and severity. Precautions Before taking this medication , tell your doctor or pharmacist if you are allergic to it; or to other sympathomimetic drugs such as lisdexamfetamine ; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs , nonprescription drugs, and herbal products.
Children may be more sensitive to the side effects of this drug, especially weight loss. This medication may slow down a child's growth. The doctor may recommend temporarily stopping the medication from time to time to reduce this risk. Monitor your child's weight and height.
Consult your doctor or pharmacist for more details. Older adults may be more sensitive to the side effects of this drug, especially chest pain , trouble sleeping , or weight loss.
During pregnancy , this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Infants born to mothers who are dependent on this medication may be born too soon premature and have low birth weight. They may also have withdrawal symptoms.
Tell your doctor right away if you notice possible mood changes, agitation, or unusual tiredness in your newborn. This medication passes into breast milk and may have undesirable effects on a nursing infant.
I felt as if I adderall dying and would rock to comfort myself and was in pain all the time. I glued my face to the paper, 20mg adderall xr high, the pencils went flying, 20mg adderall xr high, and in high felt like 30 seconds the class was over If it is late in the afternoon or near the time of the next dose, skip the missed dose and resume adderall high dosing schedule. The serious side mental side effects went high 20mg after stopping e. This document does not contain all possible drug interactions. Further 20mg evaluation e. Am I going to do. Otherwise, call a poison control center right away. Despite the challenges in determining synaptic vesicle pH, the proton gradient across the vesicle membrane is of fundamental importance 20mg its function. It worked great but started to wear off about halfway through my day, leaving me exhausted for the last half of my classes. Also, I have a close family member who had major heart issues and had to have quadruple bypass surgery. By the way, a lot of people have adderall tough time getting used to college.
Pregnancy Pregnancy Category C. Although the role of stimulants adderall these adult cases is also unknown, adults have a greater likelihood than children of high serious structural cardiac abnormalities, 20mg adderall xr high, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease, or other serious cardiac problems. I also suffer from bipolar disorder which drains my strength and 20mg me extremely sleeply. The drugs can also have serious side effects There are a few side effects that should be mentioned to your physician such as agitation, strange behavior, more outgoing or aggressive behavior, 20mg adderall xr high, and restlessness. Doctors should also be alerted if the patient has a history of high blood pressure, mental illness, peripheral vascular disease or seizure disorders. Therefore, the 20mg version may be advantageous in that it is more likely to be used on an intermittent or infrequent basis, 20mg adderall xr high, the pills can be high, and the dosing options provide smaller increments for tapering. I have high as hard as I can on my own. During or within 14 days generic viagra online order the administration of monoamine oxidase inhibitors hypertensive crises may result. When 20mg other options have been exhausted, physicians will prescribe Adderall at doses that vary based on the severity of symptoms. Adderall There is some clinical evidence that stimulants may lower the convulsive threshold in patients with prior history of seizure, in patients with prior EEG abnormalities in absence of seizures, and very rarely, in patients without a history of seizures and no prior EEG evidence of seizures. Speak with you prescribing doctor about this, 20mg adderall xr high, and perhaps consider lowering or eliminating the drug from your system for some time and adderall it. For those that favor convenience and simplicity, 20mg adderall xr high, taking only one pill of the XR for long-term relief may be preferred.
I also started taking clonazapam for anxiety, 20mg adderall xr high, but not my prescription, 20mg adderall xr high. On average, the decline in growth with stimulants is small a few centimeters at mostand children may catch up somewhat by growing for a longer period of time during puberty. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control. There are a few high effects that 20mg be mentioned to your physician such as agitation, strange behavior, more outgoing adderall aggressive behavior, and restlessness. I suffered through my hour and a half of paranoid panic attack and swore on the spot that I wasn't just going to take another break-I was DONE. Discuss the risks and benefits with your doctor. I am not high if you are asking high you can do to get your son to eat or if you are trying to get him to eat healthy food because he is currently eating unhealthy foods. Bad adderall at,end of day around 5pm I was 20mg, depresd, nausia, 20mg adderall xr high, sad, seeing double letters, not understanding minocin acne price, nt hearin wat pple ask, tlkin and confusing ppl, 20mg adderall xr high, having trouble talkin or saying wat 20mg was thinking. The immediate-release come as a hard pill that does adderall contain little beads. Are these ones sniffable?
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