Drug testing This medicine may give a positive result when testing for drug use. This includes testing used in sport. Concerta XL with alcohol Do not drink alcohol while taking this medicine.
Alcohol may make the side effects of this medicine worse. Remember that some foods and medicines contain alcohol. Tell your doctor or pharmacist if any of the above apply to you before starting treatment. The standard dosage of each drug starts at 10—20 mg per day.
However, your dosage depends on certain factors. This includes your age, other health issues you have, and how you respond to the drug. Children often take a smaller dosage than adults. Always take your dosage as prescribed. If you routinely take too much, you may need more of the drug for it to be effective. Pre-treatment screening Prior to prescribing, it is necessary to conduct a baseline evaluation of a patient's cardiovascular status including blood pressure and heart rate.
Ongoing monitoring Growth, what is concerta xl 18 mg, psychiatric and cardiovascular status should be continuously monitored see also section 4. Patients should be monitored for the risk of diversion, misuse and abuse of methylphenidate.
Posology Dose titration Careful dose titration is necessary at the start of treatment with Concerta XL. Dose titration should be started at the lowest possible dose.
A 27 mg dosage strength is available for those who wish to prescribe between the 18 mg concerta 36 mg dosages. Other strengths of this what product and other methylphenidate-containing products may be available.
Dosage may be adjusted in 18 mg increments In general, dosage adjustment may proceed at approximately weekly intervals. The maximum daily dosage of Concerta XL is 54 mg, what is concerta xl 18 mg. Patients New to Methylphenidate: Clinical experience with Concerta XL is limited in these patients see section 5.
Lower doses of short-acting methylphenidate formulations may be considered sufficient to treat patients new to methylphenidate. Careful dose titration by the physician in charge is what in order to avoid unnecessarily high doses of methylphenidate. The recommended starting dose of Concerta XL for patients who are not currently taking methylphenidate, what is concerta xl 18 mg, or for patients who are on stimulants other than methylphenidate, is 18 mg once daily.
Patients Currently Using Methylphenidate: Dosing recommendations are based on current dose regimen and clinical judgement. TABLE 1 Recommended Dose Conversion from Other Methylphenidate Hydrochloride Regimens, what is concerta xl 18 mg, where available, to Concerta XL Previous Concerta Hydrochloride Daily Dose Recommended Concerta XL Dose 5 mg Methylphenidate three times daily 18 mg once daily 10 mg Methylphenidate three times daily 36 mg once daily 15 mg Methylphenidate three times daily 54 mg once daily If improvement is not what after appropriate dosage adjustment over a one-month period, the drug should be discontinued.
Long-term more than 12 months use in children and adolescents The safety and efficacy of long-term use of methylphenidate has not been systematically evaluated in controlled trials. Methylphenidate treatment should not and need concerta, be indefinite. Methylphenidate treatment is usually discontinued during or after puberty.
The physician who elects to use methylphenidate for extended periods over 12 months in children and adolescents with ADHD should periodically re-evaluate the long-term usefulness of the medicinal product for the individual patient with trial periods off medication to assess the patient's functioning without pharmacotherapy. It is recommended that concerta is de-challenged at least what yearly to assess the child's condition what during concerta of school holidays.
Improvement may be sustained when the medicinal product is either temporarily or permanently discontinued.
Dose reduction and discontinuation Treatment must be stopped if concerta symptoms do not improve after appropriate dosage adjustment over a one-month period. If paradoxical aggravation of symptoms or other serious adverse events occur, the dosage should be reduced or discontinued.
Adults In adolescents whose symptoms persist into adulthood and who have shown clear benefit from treatment, it may be appropriate to continue treatment into adulthood. However, start of treatment with Concerta XL in adults is not appropriate see sections 4. Elderly Methylphenidate should not be used in the elderly. Safety and efficacy has not been what in this age group, what is concerta xl 18 mg. Children under 6 years of age Methylphenidate should not be used in children under the age of 6 years.
Safety and efficacy in this age group has not been established. Method of administration Concerta XL must be swallowed whole with the aid of liquids, and must not be chewed, divided, or crushed see section 4.
When used for a what time, this medication may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, concerta medication may sometimes cause addiction. Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. Psychiatric Adverse Events Preexisting Psychosis Administration of stimulants may exacerbate symptoms of behavior disturbance and thought disorder in patients with a preexisting psychotic disorder, what is concerta xl 18 mg.
Prior to initiating treatment with a what, patients with comorbid depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder; such screening concerta include a detailed psychiatric history, including a family history of suicide, what is concerta xl 18 mg, bipolar disorder, and depression.
If such symptoms occur, what is concerta xl 18 mg, consideration should be what to a possible causal role of the stimulant, and discontinuation of treatment may be appropriate.
In a pooled analysis of multiple short-term, placebo-controlled studies, such symptoms occurred in about 0. Aggression Aggressive behavior or hostility is often observed in patients with ADHD, and has been reported in clinical trials and the postmarketing experience of some medications indicated for the treatment of ADHD.
Although there is no systematic evidence that stimulants cause aggressive behavior or hostility, patients beginning treatment for ADHD should be monitored for the appearance of or worsening of aggressive behavior or hostility. Seizures There is some clinical evidence that stimulants may lower the convulsive threshold in patients with prior history of seizures, in patients with prior EEG abnormalities in absence of seizures, and, very rarely, concerta patients without a history of seizures and no prior EEG evidence of seizures.
In the presence of seizures, the drug should be discontinued. Priapism was not reported with drug initiation but developed after some time on the drug, what is concerta xl 18 mg, often subsequent to an increase in dose. Priapism concerta also appeared during a period of drug withdrawal drug holidays or during discontinuation. Patients who develop what sustained or frequent and painful erections should seek immediate medical attention.
Effects of peripheral vasculopathy, what is concerta xl 18 mg, including Raynaud's phenomenon, were observed in post-marketing reports at different times and at therapeutic doses in all age groups throughout the course of treatment. Signs and symptoms generally improve after reduction in dose or discontinuation of drug. Careful observation for digital changes is necessary during treatment with ADHD stimulants.
Further clinical evaluation e.
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