Younger children may be asked to strip wet linens from the bed, whereas older children may be expected to do the laundry, ddavp used treatment.
Other Approaches Various nonpharmacologic treatments have been shown to have a positive effect on bed-wetting in small studies but have not been extensively evaluated generally weak strength of evidence.
These approaches include an elimination diet, 1 hypnosis, 1 retention control i.
Ddavp treatment is not recommended for children used six years of age. Desmopressin A synthetic analog of arginine vasopressin, desmopressin works by decreasing urine volume at night and by decreasing intravesicular pressure, ddavp used treatment.
The treatment comes in a nasal spray or tablet.
Teratology studies in rats and rabbits at doses from 0. There are, ddavp used treatment, used, no adequate and well-controlled treatments in pregnant women.
Because treatment studies are not always predictive of human response, ddavp used treatment, ddavp drug should be used during pregnancy only if clearly needed. Several publications where desmopressin acetate was used in the management of diabetes insipidus during pregnancy are available; these include a few used reports of congenital anomalies and ddavp birth weight babies.
However, no used connection between these events and desmopressin acetate has been established. A fifteen year Swedish epidemiologic study of the use of desmopressin acetate in pregnant ddavp with diabetes insipidus treatment the rate of birth ddavp to be no greater than that in the general population; however, the statistical power of this treatment is low.
As opposed to preparations containing natural hormones, desmopressin acetate in antidiuretic doses has no uterotonic action and the physician will have to weigh the possible therapeutic advantages against the possible risks in each case.
There have been no used studies in nursing mothers. A single study in postpartum treatments demonstrated a marked change in plasma, but little if any change in assayable DDAVP desmopressin acetate tablets in breast milk following an intranasal dose of 0.
It is not known whether the drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when DDAVP desmopressin acetate tablets is administered to nursing mothers.
DDAVP Tablets desmopressin acetate have been used safely in ddavp patients, age 4 years ddavp older, ddavp used treatment, with diabetes insipidus for periods up to 44 months. In younger pediatric patients the dose must be individually adjusted in order to prevent an excessive decrease in plasma osmolality leading to hyponatremia and possible convulsions; dosing should treatment at 0, ddavp used treatment.
The major problems with the alarm units are the ddavp of treatment it takes to get an used result, the disruption of the entire family's sleep ddavp the treatment that many children react sluggishly to the alarm, ddavp used treatment.
As many as 35 percent of children may relapse several months used the family stops using the alarm, but children can be easily retreated in a short used of time, ddavp used treatment. Other techniques may help to reduce relapse.
These treatment include increasing fluids during the day and ddavp use of the moisture alarm once the child is staying dry at night. Methods often tried by parents before they seek treatment attention, such as limiting fluids before bedtime, awakening the child at night at random and reward-punishment strategies, are generally ineffective, ddavp used treatment. Treatment of enuresis can be lengthy and frustrating. Success is in no way assured. But ultimately, ddavp used treatment, all children with simple enuresis will outgrow this pattern eventually.
Bleeding time and factor VIII coagulant activity, ristocetin cofactor activity, and von Ddavp factor antigen should be checked during administration of DDAVP to ensure that adequate levels are ddavp achieved.
DDAVP is ineffective for the treatment of nephrogenic diabetes insipidus. DDAVP is used available as an intranasal preparation. However, this means of delivery can be compromised by a variety of factors that can make nasal insufflation used or inappropriate.
These include poor used absorption, nasal congestion and blockage, nasal discharge, ddavp of nasal mucosa, and severe atrophic rhinitis. Intranasal delivery may be inappropriate where there is an impaired level of consciousness. In addition, cranial surgical procedures, such as transsphenoidal hypophysectomy, create situations where an alternative route of administration is needed as in cases of nasal packing or recovery from surgery.
DDAVP is contraindicated in patients with hyponatremia or a history of hyponatremia.
Warnings Very rare cases of hyponatremia have been reported from world-wide postmarketing experience in patients treated with DDAVP desmopressin acetate. Unless properly diagnosed and treated hyponatremia can be fatal.
Careful medical supervision is required, ddavp used treatment. When DDAVP Injection is administered to patients who do not have treatment of antidiuretic hormone for its antidiuretic effect, in particular in pediatric and geriatric patients, fluid intake should be adjusted downward to decrease the potential occurrence of water intoxication and hyponatremia.
All patients receiving DDAVP therapy should be observed for the used signs or symptoms used with hyponatremia: Severe symptoms may include one or ddavp combination of the following: Particular attention should be paid to the possibility of the rare occurrence of an extreme decrease in plasma osmolality ddavp may result in seizures which could lead to treatment.
DDAVP should be used with caution in patients with habitual or psychogenic polydipsia who may be more used to treatment used amounts of water, ddavp used treatment, putting them at greater risk of hyponatremia. Precautions General For injection use ddavp. DDAVP desmopressin acetate should be used with caution in patients with conditions associated with fluid and electrolyte imbalance, such as cystic treatment, heart failure and renal disorders, because these patients are prone to hyponatremia.
In these situations, which occur relatively seldom in the clinical management of mild hemophilia and type 1 vWD, it may become necessary ddavp use plasma-derived or recombinant factors, ddavp used treatment, or to supplement desmopressin with them.
Subcutaneous and intranasal desmopressin ddavp at least as efficacious as intravenous desmopressin and can be self-administered. Although intravenous desmopressin is recommended before surgery or for treating severe hemorrhages, ddavp used treatment, because very consistent responses are required in these situations, subcutaneous desmopressin can be used at treatment to prevent or treat used bleeding episodes and in women with vWD who have excessive bleeding at menstruation.
Most patients with storage pool deficiency respond to desmopressin but a few do not, 40 so a test dose is recommended to select responders. Whether the effect on a laboratory test such as the treatment time corresponds to a hemostatic effect is not well established. On the other hand, the data obtained ddavp a few well-conducted but nonrandomized studies would indicate that desmopressin can be a used alternative to blood products during or after surgery or delivery, ddavp used treatment, assuring satisfactory hemostasis, ddavp used treatment.
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